The traditional HPC and commercial markets have been converging as established HPC users increase their use of newer analytics methods and commercial firms turn to HPC for mission-critical analytics problems that enterprise technology alone can’t handle adequately. Key verticals exploiting HPDA include financial services, healthcare/bioinformatics, energy, cybersecurity/fraud, manufacturing, online retailers and service providers, digital content creation, telecommunications, government, and academia. Key horizontal applications include simulation, fraud and anomaly detection, business intelligence/business analytics, machine learning/deep learning, affinity marketing, and advanced visualization.